Genetically engineered bacteria armed with CRISPR could help combat antibiotic-resistant infections and also allow doctors to edit people’s microbiomes



Health



5 November 2021

Antibiotic-resistant strains of E. coli bacteria can be targeted with a CRISPR-based weapon

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A benign bacterium armed with a designer CRISPR-based weapon has been used to eliminate a harmful bacterium from the guts of mice while leaving all other microbes unharmed.

The approach could give us a new way of tackling antibiotic-resistant infections of the gut and skin, says Sébastien Rodrigue at the University of Sherbrooke in Canada, and also help treat a wide range of diseases by editing the microbiome.

Others have shown this approach works in …

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